IGFL

@igflyon.bsky.social

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A strong focus on integrative, organism-level research at the interfaces of evolution, development & integrative physiology studied in lots of model systems igfl.ens-lyon.fr

Catherine Dulac presenting her work on social isolation
Annonce officielle de l’IGFL pour le recrutement du poste cité ci-dessus
White IGFL seminar flyer. Top left: IGFL logo in pink. Center top: title “External seminars – IGFL” above a stylized blue question mark. Speaker name: Anamaria Necsulea. Laboratory of the speaker: Laboratoire de biométrie et biologie évolutive (LBBE, Lyon). Invited by: Eglantine Heude. Date: 29/01/2026. Title: “Convergent evolution of genomes and phenotypes in birds.” Abstract summarizes comparative and functional evolutionary genomics in birds, focusing on convergent phenotypic evolution. Main case study: repeated reduction or loss of the intermittent male phallus in multiple avian lineages. The work analyzes hundreds of bird genomes to identify parallel changes in protein-coding genes, non-coding regulatory elements, and gene expression associated with this developmental and evolutionary transition. Bottom section: short CV detailing PhD (University of Lyon), postdoc in Lausanne, junior group leader at EPFL, and current CNRS researcher at LBBE studying evolution of gene regulation and phenotypes. Right side: portrait photo of the speaker outdoors, smiling, short hair, wearing a dark top.
Flyer announcing a seminar by Jean Livet from the Institut de la Vision, hosted by Jonathan Enriquez at IGFL Lyon on June 30th, 2025. The talk is titled “Topography and topology in a central sensory neuronal projection.” The abstract explains that in the vertebrate brain, sensory pathways connect neuronal relays with high precision over long distances. To study these circuits, dense single-neuron tracing and large-volume microscopy are used. Jean Livet will discuss their efforts in connectomic mapping using multicolor labeling, focusing on an auditory relay to reveal its topographical and topological organization. The flyer also includes a short bio: Jean Livet completed his PhD on motor neuron development at IBDM Marseille, developed the Brainbow labeling method during his postdoc with Jeff W. Lichtman in the USA, and has led the “neurogenesis and circuit development” team at the Institut de la Vision since 2008.
Cartoon of Steven Van Belleghem riding a giant beetle over green islands, holding a camera and flying scientific papers. A hawk and butterfly accompany him, symbolizing his evolutionary genomics research on butterflies, Daphnia, and beetles.
The drosophila brain
Title of the presentation Metabolic flexibility of the Drosophila nervous system Short abstract Neuronal function consumes large amounts of energy. This energy needs to be provided in order to maintain homeostasis. To deal with this disproportionate demand, glial cells support neurons metabolically. Like their mammalian counterparts, Drosophila glial cells are very glycolytically active and provide lactate to the neurons under optimal conditions. Upon suboptimal conditions, several aspects of brain metabolism can be adapted. On the one hand, nutrient uptake into the nervous system is regulated to ensure nervous system function. On the other hand, glial cellular metabolism can adapt to changing conditions. E.g. when carbohydrate supply is not sufficient to meet the metabolic needs of the neurons, the glial cells switch to ß-oxidation of fatty acids and produce ketone bodies as an alternate fuel that they supply to neurons. It turns out that glial metabolism can be adapted to different conditions, like starvation or cold exposure, in different ways to ensure neuronal function. Short CV Stefanie Schirmeier graduated from the University of Bayreuth (Germany) and joined Dominique Ferrandon’s team at the University of Strasbourg (France), where she studied host-pathogen interactions using Drosophila melanogaster as a model. She contributed to a genome-wide genetic screen and discovered the compensatory proliferation of intestinal stem cells in response to gut infection, as well as identifying a bacterial virulence factor required to counteract the cellular immune response. She then moved to the University of Münster (Germany) for a postdoctoral position, joining Christian Klämbt’s team and later establishing her own research group there. Stefanie focused on investigating the physiology and metabolism of glial cells and uncovered their role in neuronal nutritional support via the astrocyte-neuron lactate shuttle. Since 2021, Stefanie has been a professor at Dresden Technic…
Poste à pourvoir d'IE en microscopie et immunohistochimie à l'IGFL. Plus d'infos: filipe.de_vadder@ens-lyon.fr.
Poste d’attaché•e de direction à l’IGFL. Pour plus d’informations contactez direction.igfl@ens-lyon.fr.
De l'océan au laboratoire: à la rencontre des organismes modèles marins