adam grieve

@adamgrieve.bsky.social

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Membrane protein signalling and turnover in neurons Sir Henry Dale Fellow at School of Biochemistry, University of Bristol grieve-lab.com

An equilibrium molecular dynamics simulation of a human rhomboid protease (RHBDL2, blue). This view looks through the lateral gate helices, which substate must pass through to gain access to the active site (in red). The lateral gate is highly dynamic in some rhomboids, but not in others.