Anke Sparmann

@ankesparmann.bsky.social

81 Followers 107 Following

Scientific writer @helmholtz-hiri.bsky.social and editor at Life Science Editors (https://www.lifescienceeditors.com/)

Cartoon depiction of the antisense oligomer approach to silence transcripts from phages in infected bacteria. In the top left, a bacteriophage infects a bacterial cells and injects its DNA, which is transcribed into an mRNA and expressed into a protein. In the top right, antisense oligomers (shown in red) delivered into the bacterium bind to the target phage mRNA and prevent synthesis of the phage protein. If the encoded protein is essential, phage replication and bacterial cell lysis (shown on the bottom right) are halted and the bacterium is protected, depicted by a red shield (bottom left).
Winter aconites in the sun, grass and dried leaves in the background