Base by Base

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Where genomics meets sound Music & podcasts inspired by research 👇 basebybase.com

Base by Base cover: E. coli TGT binds two tRNAs — cryo-EM reveals dual engagement
Base by Base cover: High‑coverage genomes recast Japan's prehistoric demography
Base by Base cover: Lactate, HSP90α and the Mitochondrial Switch
Base by Base cover: Echovirus 18: Capsid opening releases the genome
Base by Base cover: KIAP4 and the ARND family: essential proteins for Leishmania–sand fly adhesion
Base by Base cover: Proterozoic Rise: Steady Diversification of Crown Eukaryotes
Base by Base cover: Validating the EAGL genetic literacy measure
Base by Base cover: Genetic regulation of plasma metabolites in people with HIV
Base by Base cover: When Genes Talk to Gut: Microbiome as Mediator of Metabolic Risk
Base by Base cover: ProtoCloud — Prototypical self-explaining model for single-cell analysis
Base by Base cover: BEAM: Bayesian reconstruction of metastatic migration histories
Base by Base cover: LECA's Ancient Interactome and Modern Disease
Base by Base cover: How GRN Topology Shapes the Genetic Architecture of Expression
Base by Base cover: Germline rDNA Variants and Human Complex Traits
Base by Base cover: Pre-existing Cell States Predict Multi-Treatment Resistance
Base by Base cover: NOTCH2NL duplications: diversity, regulation, and human-specific changes
Base by Base cover: The Single-Cell Pediatric Cancer Atlas
Base by Base cover: Translating GWAS Across Scales
Base by Base cover: Hidden Mosaic: Parental Postzygotic Mutations in 12,015 Trios
Built with Claude: Life Sciences — hackathon acceptance
Base by Base cover: HGT-chimeras: fusion across the tree of life
Base by Base cover: ERG Unlocked: Targeting the PNT Domain with PBITE-1
Base by Base cover: Durability of Cas9 Gene Drives in Anopheles: A 2‑Year Cage Study
Base by Base cover: Rpc34 WH2 dynamics in RNA polymerase III
Base by Base cover: Fault Lines in Forensic Proficiency Testing
Base by Base cover: EKV cells and the Human Prion Assay: a scalable platform for sCJD infectivity
Base by Base cover: Nucleotide diversity is a poor predictor of short-term adaptive potential
Base by Base cover: A systems-level atlas of carbon-response transcriptional states in Escherichia coli
Base by Base cover: Tau, mitochondria, and the fusion switch
Base by Base cover: SLC11A2 withholds metals from Salmonella in the gut epithelium
Base by Base cover: Temperature & Age Shape Gut Susceptibility to HCoV-229E
Base by Base cover: PRDM9 and the Hotspot Trade-off
Base by Base cover: RUNA Reveals Surface DNA on Exosomes
Base by Base cover: HRD-GIS Evidence for BRCA1/2 Variant Classification
Base by Base cover: When Polygenic Scores Miss: Rare Variants in Misaligned Individuals
Base by Base cover: LDB1 variants split neurodevelopmental outcomes by location and mechanism
Base by Base cover: Complete chromosome 21 centromere sequencing and Down syndrome
Base by Base cover: Base by Base 399 — Ménière disease: inner ear development and retinoic acid pathways
Base by Base cover: SciPhy: Bayesian phylogenetics for sequential genetic lineage tracing
Base by Base cover: Physical homology recognition between DNA duplexes
Base by Base cover: Extended sequence context shapes mutational bias in Escherichia coli
Base by Base cover: Benchmarking LLMs for cfRNA biomarker discovery
Base by Base cover: Hidden Resistance: tNGS Reveals Rifampicin and Bedaquiline Resistance in Eswatini
Base by Base cover: GWAS of Cocaine Self-Administration in Heterogeneous Stock Rats
Base by Base cover: The Kaufmann Protocol — Why We Age and How to Stop It
Base by Base cover: Daunorubicin, Mutual Destruction, and Layered Antiphage Defense
Base by Base cover: Crotonylation impedes c-Myc oncogenic activity
Base by Base cover: Base by Base | Episode 388 — In situ CAR‑macrophage alleviates liver fibrosis
Base by Base cover: Homotypic Dengue Reinfections and Long-Term Antibody Decay
Base by Base cover: Genome Doubling and the Bioeconomy
Base by Base cover: Growth under Pressure: Polyploidy Induced by Stress
Base by Base cover: RNA Brake on Cholera Phage: CisR Controls CTXÏ•
Base by Base cover: Genetics of the Circulating Proteome: pQTLs, Pathways, and Disease Links
Base by Base cover: How animal blood cells evolved from unicellular ancestors
Base by Base cover: Light-written spatial barcodes enable tunable multiomic sequencing (BALI)
Base by Base cover: Prime-SGE maps drug-resistance variants at scale
Base by Base cover: Long reads reveal hidden structural and repeat variation in autism
Base by Base cover: Dominant-negative PSMB8 variants stall immunoproteasome assembly
Base by Base cover: ProteomeLM — proteome-scale language modeling for interactomes and essential genes
Base by Base cover: Pfh1's Balancing Act: Unwinding, Rewinding, and the Role of Mitochondrial SSB