Castañeda Lab at SU

@castanedalab.bsky.social

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Using molecular biophysics, biochemistry, and cell biology to understand the intersection of protein quality control mechanisms and neurodegenerative disorders (ALS, FTD); IDPs, Ub biology, UBQLNs

Transfected UBQLN2 constructs containing residue numbers listed in the absence and presence of heat stress.
Live-cell imaging of UBQLN2 constructs in the absence and presence of heat stress
Simulation of how STI1 (red) may engage with internal IDR regions (orange) of yeast shuttle protein Dsk2
BMB interest group speakers include Jeanne Stachowiak, Trever Bivona, Heather Meyer, and Lalit Deshmukh!
SU Biology Department - Fall 2023
Effects of different epitopes on full-length UBQLN2 or UBQLN4 phase separation visualized via temperature-concentration phase diagrams.
SU at ABRCMS
Inside LSC