Roberto Chica Lab

@chicalab.bsky.social

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Our research group at the University of Ottawa specializes in computational enzyme design. mysite.science.uottawa.ca/rchica/

Announcement for the 6th Protein Engineering Canada Conference, to be held June 22nd-24th in Ottawa, Canada. The image shows a protein structure in front of a picture of Parliament Hill and Chateau Laurier in Ottawa.
The crystal structure (blue) aligns closely with the design model (minimal TIM barrel and lid colored white and magenta, respectively).
Michaelis-Menten plot of KempTIM4 showing saturation kinetics.
Building a custom lid onto a minimal, de novo TIM barrel using CANVAS.
De novo enzyme design using CANVAS.