Dave Grainger

@degrainger.bsky.social

1524 Followers 703 Following

Developmental biologist studying endothelial cell differentiation and heterogeneity Postdoc in the Stone Lab - Institute of Developmental and Regenerative Medicine, Oxford, UK

Picture from the edge of a cliff looking along the coast with dark grey rocks sticking out of a turbulent aqua marine sea with lots of foam
A woman and a man standing next to eachother in a black and white room. An optical illusion makes the woman appear twice the height of the man
Comic book style drawing of a red formula 1 car driving on a race track with green mountains in the background and orange flowers in the foreground. Written on the floor next to the F1 car is written Spa Francorchamps
A vibrant abstract image with a network of lines in blue, purple, yellow, and red against a white background. Shape resembles a medical illustration of a woman with a painterly effect
Three happy people wearing Gloucester rugby jersey's (cherry and white stripes) stood in front of a rugby pitch.
Left side shows confocal images of immunostained transverse vibratome sections from E9.5 mouse embryos. In green, endothelial cells of the cardinal vein (CV) and dorsal aorta (DA) are labelled with EMCN. Pax3-Cre lineage labelled lymphangioblasts are stained for ETV2 and PROX1 dorsal to the CV. On the right, an RNA-FISH stained embryo is shown in wholemount. Endothelial cells, stained in green with Pecam1 are throughout the embryo, Lbx1+ hypaxial dermomyotome is shown in the ventral aspect of somites. A boxed region of ~4th somite is enhanced to the right showing Etv2+ lymphangioblasts within the hypaxial dermomyotome.
Scientific figure showing force atlas embedding of scRNA-seq data with cells coloured by celltype (e.g. LEC, angioblast, arterial EC) at the top and coloured by Etv2, Pecam1 or Prox1 expression on the bottom
Timeline of mouse embryonic development between embryonic day 9.5 and 11.5. Each timepoint has a schematic of a mouse embryo with paraxial mesoderm derived (Pax3-Cre;Rosa26-tdTomato) tissues (e.g. somites) in magenta and non-PXM derived ECs in green. Below the timeline arrows show that endothelial cells are FACS sorted for scRNA-seq.
A large tree at night covered in white Christmas lights