Wendy Xin

@droligo.bsky.social

852 Followers 328 Following

馃嚚馃嚘 Scientist and Assistant Professor at UHN/University of Toronto 路 oligodendrocytes & myelin | synapses & circuits | neurodevelopment 路 BSc UofT -> PhD Johns Hopkins -> Postdoc UCSF 路 she/her www.oligodendrocyte.org

Toronto skyline in a haze of smoke
A flyer displaying the same information as written in the post, with two images of two astrocytes around a blood vessel and one newly formed oligodendrocyte, along with logs our sponsors Avantor and Plasmidsaurus.
Fluorescently labeled astrocytes at varying distances from cortical or white matter stroke infarct border
Example spinodendrograms in visual cortex, showing more spatial clustering of spine changes following deprivation in mice with impaired adolescent oligodendrogenesis
Example in vivo images of dendritic spines in visual cortex
Quantification of visual cortex responses following monocular deprivation in control mice. There is a decrease in responses to visual stimulation of the contralateral (deprived) eye.
Quantification of visual cortex responses following monocular deprivation in control mice. There is no change in responses to visual stimulation of the contralateral (deprived) eye
Images and quantification of oligodendrocyte and OPC density in control and experimental mice. Oligodendrocyte density is significantly lower and OPC density is unchanged in experimental group.
Images of oligodendrocyte lineage cells in contralateral and ipsilateral visual cortex during adolescence, following monocular deprivation. There are fewer cells generated following deprivation in the contralateral cortex.
Microscope image of myelin and oligodendrocytes in visual cortex