Edda Schulz

@eddaschulz.bsky.social

872 Followers 345 Following

Group Leader at MPI Molgen, Berlin, Germany Interested in quantitative biology, gene regulation, epigenetics, system biology and X-chromosome inactivation. https://www.molgen.mpg.de/schulz-lab

Top: scheme of synthetic antisense locus; bottom: experimental setup where a Dox pulse induces antisense-mediated repression that leads to a sustained down-regulation of the sense gene.
genome browser tracks of nascent transcription of the region surrounding the Nfatc4 gene for 3 time points: at day 0 transcription mostly comes from an antisense transcript, which disappears at day 4, where the Nfatc4 gene now is transcribed.
Scheme of convergent antisense locus and scheme of expression memory where one antisense partner is high and the other one is low until they switch and memory is lost.
Poster advertising the 6th X-inactivation meeting from Oct 19-23 2026 in Sapporo, Japan. The organizers are Asato Kuriowa, Edda Schulz, Ikuhiro Okamoto, Rafael Galupa, Takashi Sado, Mitinori Saitou.
Violin plots showing the fraction of X-linked reads coming from the inactive X as a function of Xist expression level. The plot shows that lower Xist expression results in weaker X-chromosome silencing.