Gerlich Lab

@gerlichlab.bsky.social

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We study how genomes change shape to make biology work through genomics, imaging, reconstitution, & computation. Lab website: oeaw.ac.at/imba/research/daniel-gerlich Located at @imbavienna.bsky.social, part of @viennabiocenter.bsky.social

Alt text for the pic: Model depicting sister chromatid organization as defined by TAD hierarchy.

Left: average profiles of Sororin (upper panel) and RAD21 (lower panel) ChIP-Seq signal (1 kb resolution) at ±100 kb regions centered at high-, mid- and low-level boundaries. Right: average maps of trans sister (upper row) and cis sister (lower row) scsHi-C contacts (10 kb resolution) at ±1 Mb regions centered at high-, mid-, and low-level boundaries, normalized to genome-wide expected contact frequencies.

“Maximilian Spicer holding the Best Poster Prize certificate at the 2nd Spatial Genome Organization Conference.”