Ken Halvorsen

@halvorsenlab.bsky.social

234 Followers 167 Following

Mostly posting science from our lab at RNA Institute, UAlbany.

Abraham Punnoose, J., Cole, D., Melfi, T., Morya, V., Madhanagopal, B.R., Chen, A.A., Vangaveti, S., Chandrasekaran, A.R., & Halvorsen, K. (2025). Tuning the Stability of DNA Tetrahedra with Base Stacking Interactions. Nano Letters 25, 3605-3612. PMCID: PMC11887421. [R35GM124720 for JAP, DC, VM, and KH (sole support for Halvorsen lab – concept, design, execution, analysis of tetrahedron experiments); other authors: R35GM133469 for TM, SV, and AA (MD simulations); R35GM150672 for BRM and ARC (DLS and AFM experiments)]
Design of a dual detecting DNA nanoswitch where aptamer binding of a protein target causes a loop of a specific size to form. When read on gel electrophoresis, two proteins can be detected simultaneously, in this case VEGF producing a large loop and thrombin producing a smaller loop.
images of a conventional gel box and 3D printed mini boxes with resulting gel band images
large crates packed with science equipment
A terrible AI image of an interdisciplinary triangle that is actually a circle