The Jackson Laboratory

@jax.org

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Est. 1929, JAX is a nonprofit scientific research institute specializing in genetics, genomics, mouse, and cellular models of disease. www.jax.org

a microscopy image of dopaminergic (DA) neurons. Blue lines with redish cells on a black bacground
Cover of a publication with the title "Beyond the Barrier." Below is a subtitle, "A new model for late-onset Alzheimer’s driving critical momentum in research." The background includes scientific imagery.
Cover of a publication with the title "Beyond the Barrier." Below is a subtitle, "A new model for late-onset Alzheimer’s driving critical momentum in research." The background includes scientific imagery.
An abstract digital representation of a DNA strand composed of blue pixelated dots on a dark blue background. Text reads: "The Jackson Laboratory wins highest prize in global ed tech competition. JAX Biomedical Pathways awarded $300,000, funding a two-year project delivering workforce readiness for students.
Promotional image for the JAX-NYSCF Conference, taking place September 23-24, 2026, at The Rockefeller University, New York. The text encourages registration and highlights the focus on advancing translational stem cell science.
A group of people standing outdoors in front of a brick building with white pillars, smiling at the camera. They appear to be a diverse group.
Promotional image for the JAX-NYSCF Conference, taking place September 23-24, 2026, at The Rockefeller University, New York. The text encourages registration and highlights the focus on advancing translational stem cell science.
A quote from JAX Senior Research Scientist Francesca Menghi, Ph.D.: "The big picture of our work is public health, because we have identified a new risk factor that potentially accounts for about a quarter of two very aggressive types of female cancers."
A cross section of a mouse brain. Text reads: Precision DNA editing targets root cause of severe childhood epilepsy in preclinical study It's the latest breakthrough from a collaboration advancing gene editing towards real-world treatments for rare disease
Molecular maps of mouse brain tissue created by spatial transcriptomics. There are 12 brains on a black background. Each color represents a distinct cellular neighborhood shaped by unique genetic activity. By mapping these neighborhoods across healthy, aging, and diseased brains, JAX scientists are uncovering how Alzheimer’s disease spreads through critical brain regions involved in memory and cognition. To generate these images, researchers measured the activity of 247 genes in each brain slice using the 10x Genomics Xenium In Situ platform. Using an unsupervised machine learning approach called K-means clustering, the team grouped regions with similar molecular signatures. Even without anatomical instructions, the algorithm naturally recreated recognizable brain structures.
Three individuals are featured against a dark background with the title, 'What do these cancer research pioneers have in common?' The JAX logo is present in the lower corner.
A group of individuals standing in a well-lit hallway, at the JAX campus.
The image is an advertisement for the Edward H. and Connie Birkenmeier Distinguished Lectureship in Genetics and Evolution, titled "BATS: New Models of Extended Healthspan and Disease Resistance." It will take place on April 27, 2026, from 4-5 P.M. ET, available virtually or in Bar Harbor, Maine. Featuring Dr. Emma Teeling, Professor at University College Dublin, School of Biology and Environmental Science. The background features small bat images.
A photo of three scientists with text below. Text reads: Spotlight on the 2026 Brooks Scholars The Brooks Scholar Award supports innovative research projects to unravel the connection between cancer and aging.
A quote from JAX professor and geneticist Michael Stitzel, PhD. It reads: "This is a huge problem. Almost everyone knows someone affected by diabetes. We really have to think about the fact that there are many ways the disease can arise, which means there should also be many ways to target it. As a gene hunter, identifying the genes that contribute to disease is exciting because it gives us actionable information for precision medicine."