Joe Peters Lab

@joepeterslab.bsky.social

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Professor and Chair, Dept Microbiology Cornell Ithaca. Interested in genome evolution and mobile DNA, especially Tn7 and CRISPR-Cas transposition systems

Mike Petassi presenting a slide

Christmas cactus in partial bloom

Cartoon diagram indicating a mechanism that would allow a I-E CRISPR-Cas system to degrade the subtelomeric region while allowing the transposition machinery to be recruited and direct transposition into these regions.

Similarity tree of TniQ proteins in Streptomyces showing the relationship to known telomere maintenance and telomere conjugation proteins.

Figure displays a similarity tree of DDE transposases in Streptomces on the left. On the right the position and orientation of each element is indicated with a dot indicating their position relative to central origin of DNA replication and the telomere. Two branches show a distinct bias to the telomere and for integration in a single orientation.

Diagram comparing the gene arrangement found with PAST elements and another branch of elements that also branches within the type V-K CAST elements

Similarity tree showing the relationship between type V-K CAST elements and the newly identified PAST elements that associate with protelomerase in bacteria