Jonas Verhellen

@jonasverhellen.bsky.social

1693 Followers 2097 Following

Theoretical physicist with a PhD in neuroscience. Postdoc in protein-protein interactions. Into art, science, and innovation. Currently: Copenhagen 🇩🇰 Previously: Oslo 🇳🇴, London 🇬🇧, Brussels 🇧🇪

People playing the board game "Tokado" with candles in the background.
Severe Mental Disorders Affect The Entire Body. Severe mental disorders are characterised by their detrimental effect on brain functioning (shown in blue), but patients suffering from these diseases are also disproportionately affected by a range of other diseases (shown in red). For each cluster of diseases comorbid with schizophrenia or bipolar disorder, we highlight a representative organ and provide the 95% confidence interval mortality risk ratio in incident and prevalent schizophrenia cases versus the general population.
A figure illustrating the frequency spectrum of genetic risk factors for schizophrenia, with three categories represented by distinct colors: blue for common variants, red for protein-truncating variants, and green for copy number variations (CNVs). Each category is paired with a representative gene: C4A for common variants, SETD1A for protein-truncating variants, and NRXN1 for CNVs.
A graph illustrating the typical onset and progression of schizophrenia over time, with age on the x-axis and symptom intensity on the y-axis. A blue line represents symptom intensity, starting low in early childhood, increasing during adolescence, and peaking in early adulthood. Red boxes along the timeline highlight risk factors such as genetic predispositions and environmental triggers. White boxes mark key milestones in disease progression, including the prodromal phase, first psychotic episode, and chronic stages. A green-shaded area indicates a "window of opportunity" for early intervention, occurring before symptom intensity sharply increases.