Korak Ray

@korakray.bsky.social

153 Followers 205 Following

Interested in biophysical chemistry, single molecules, and nucleic acids. Into puns and speculative fiction. Postdoc @Rueda Lab, MRC LMS. He/him

A range of DNA structures found within ultrafine bridges (Holliday junctions, replication forks, overstretched dsDNA, catenations) highlighting stretched junctions that can these structures that can be cleaved by ANKLE1
Plot showing increase linear increase in the log of cleavage rate with increasing tension
Two panels showing ANKLE1 cleavage of DNA held between optically trapped beads. The left shows slow cleavage at low tension, and the right shows fast cleavage at high tension.