IMAGE Lab

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B cells | Macrophages | Immunity | Autoimmunity | Cancer | Osteoclasts | Osteomorphs | Intravital imaging | Precision Immunology

Lab Big Day Out June 2025! On ferry to Manly on a cold winter's day!
Serum neutralising antibody levels against ancestral, Delta and Omicron variants.
Flow cytometric analysis of fine needle biopsies from healthy participants with vaccine boost in the same compared to opposite arm.
Experimental design of clinical study comparing boosting of the COVID mRNA vaccine in the same or opposite arm of healthy participants.
Experimental design and enumeration of the recall response in non-draining lymph node that had been 'primed' with an irrelevant, non-cognate antigen.
Heatmap and violin plots showing differentially expressed genes between memory B cells in the draining lymph node, non-draining lymph node and spleen and naïve B cells in the lymph node and spleen.
Flow cytometric analysis showing impaired recall response and GC re-entry in the draining lymph node when subcapsular sinus macrophages are depleted with anti-CSF1R mAb.