MattWolf-PhD

@mattwolf-phd.bsky.social

193 Followers 33 Following

Immune modulatory biomaterials for treating cancer and cancer patients. Biomaterials Scientist, Tissue Engineer, & Cancer Immunologist for the low, low price of a Biomedical Engineer. Interesting views and opinions are my own.

Cover art for May issue of Cancer Research featuring immunofluorescence of our lab's "MatriSphere" 3D tumor model of extracellular matrix-tumor cell interactions.
The Cancer Biomaterials Engineering Section at the National Cancer Institute (NCI) is hiring a Postdoctoral Fellow to lead projects in developing implantable biomaterial scaffolds for tissue repair and cancer immunotherapy delivery. The Lab is headed by Dr. Matthew Wolf and is located at NCI Frederick, MD. It is a multidisciplinary combination of biomaterials science, cancer immunology, and tissue engineering. The Lab studies immune modulatory scaffolds as a local delivery system for cancer immunotherapy after surgery and as 3D scaffolds for building immune competent tumor models in vitro. Naturally derived materials composed of decellularized extracellular matrix are of particular interest. Our long-term mission is to design biomaterial scaffold-based strategies that modulate and enhance antigen specific anti-tumor immune responses after surgical tumor resection. Interested candidates should email a brief cover letter, CV, 2 first-author publications, and contact information for 3 references to matthew.wolf@nih.gov. The cover letter should include research experience, career goals, interest and expectations, and preferred start date. Positions are available in Fall 2025. Candidates with experience & interest in the following areas are encouraged to apply: • Animal models: transplantable tumors and soft tissue surgery • 3D in vitro models such as tumor organoids or spheroids • Immunology / cancer immunology • Biomaterial scaffold design and characterization • Spectral flow cytometry • Immunofluorescence/IHC tissue staining • Single-cell sequencing and analysis • Tissue engineering Qualifications: Postdoc applicants are expected to hold an advanced degree (M.D., Ph.D) in Biomedical Engineering, Chemical Engineering, Immunology, Chemistry, Biology, Materials Science, or related fields. Those with expected graduation dates in upcoming semesters may also apply. Posting date July 3, 2025, and applications will be accepted until the position is filled.