Mark Cuban @mcuban.bsky.social · Mar 22 From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA
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The pharma companies are oddly quiet about all this.
I’m 42 & have metastatic lung cancer. Meeting this week with leaders in the lung cancer research community & my patient group to discuss strategies for how we break into the general public’s awareness about what continuity of NIH funding means for our survival. Long shot but we’d love your help.
It’s pretty simple. Private corporations won’t do research that doesn’t have (nearly) immediate profits. We need publicity funded research to take on the hardest long term studies.
The insidious thing is that the real damage will come years down the road. Pharma can keep developing "me too" drugs, but with basic research funding cut off, there will be no breakthroughs coming out of the U.S. once those currently in the pipeline are out.
Yet the pharmaceutical companies claim they need to charge exorbitant prices so they can develop new drugs. Bullshyt. The spend more on advertising, marketing and executive compensation than they spend on research, and most of the research they do is market research.
The goal is just to get rid of the FDA and allow drug manufacturers to sell whatever they want and not be liable for any damages to their customers.
Just another example of why we need to organize !
We care but the current Republican Administration doesn't. Hopefully they suffer first and most from their poor leadership and decisions.
Rather than shrinking away from science, 4whatever idiotic reason we r doing that, let's put hooks in the grants w royalties on commercialization. It's done when licensing tech out of one of the universities. It can be done, we did something like this on some tech out of Brookhaven Labs years ago.
Wow! So these folks will be scooped up and the brain drain from the US will be considerable. Is this what anyone wanted/voted for?
Mark -- We need you in the Shadow Cabinet. Can you please push @kenmartin.bsky.social to set up a Shadow Cabinet with you as the Shadow Secretary of Commerce? Dems don't understand that we need a new strategy and different tactics to win this fight.
Taking away NIH funding not only makes us less safe because it slows down research & development of new drugs, but also undermines America's competitive advantage in medical & all other peripheral practices. Donald's deliberately doing what an enemy would do. youtu.be/yVK75OHqDXo
@mcuban.bsky.social yes, and so much more. we were the envy of the world for our biomedical research.
The NIH is the foundation for medical and scientific research funding. Without it there won’t be research, EXCEPT for the privately funded. You know, the kind where the big pharma companies do “research” on their own drugs. How could that be a conflict?
The cut will set us back so so far & many people will die needlessly. It’s heartbreaking how selfishly cruel this regime is.
How about some Cod liver oil and Ivermectin with 3oz of Absolute?
Death Panels - that’s the plan. On every front, he wants to kill Americans. From not providing safe foods to gutting NIH to not testing for fecal material or poisons in the water to eliminating food programs for children (which also causes farmers to go bankrupt) Destroy destroy destroy.
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Not only is this a demonstration of how very important the National Institute of Health is, it also demonstrates how ridiculous it is that our taxes pay to develop drugs and when they hit the market we pay more for them than any other country on the planet.
Yep. We might be coming up with druggable targets, while the industry comes up with the drugs. Sometimes it works even better, and there's a drug (even a generic) which works on that target, which can be repurposed (off-label use).
Not anymore.
excuse me I apologize if I'm a little behind but.... does this mean Trump is cutting the national institute of health?! I mean I wouldn't be surprised at all... I wonder what he's not going to take away?
I spoke to a neurosciences researcher, recently, who said they are looking for other sources of funding. Beyond drug dev, research supports of global health.
That must be where the fraud & waste is because why would you want to save any lives.
Corporations do not look for cures. Corporations look for money making schemes, for long term dependency. The NIH looks for real treatments and cures. Corporations only look for huge profit margins and ignore research when they don’t think it will make them richer.
You've been in the pharma realm recently. Perhaps you'd like to restart a few closed clinical trials?
Maga cutting research dollars will make America less competitive in the global economy for decades
Why do our natural resources get owned by private companies, that's our oil. Why do tax dollars pay for research and then a private company gets to make profits. Sounds like America's government is fucking over everyone who lives there
Such a vital agency and brain drain…
The economics of basic research as opposed to applied research, and why one requires the public investment in the other. If Americans were better educated in science, there would be more support for basic research in so many areas. It’s what can fuel our progress and our economy.
It’s almost like the NIH is important and maybe deserves public funds?
We need to amplify stories of patients having treatment stopped because of these cuts. People will die and they need to be remembered and shoved in these assholes’ faces
Come on Mark. You're smarter than this. Ignoring the stats on recalled drugs, researched with grants from NIH, is an issue. The FDA isn't a saintly organization. Not by a long stretch. www.lightfootlawdc.com/blogs/fda-dr...
They don't care
Let's also remember that Team Idiocy also cut the FDA as well. Between these two, the USA will go from a top Bio/Pharma hub to zilch, further destroying the economy. Biopharma rev is predicted at about 510Billion for 2025.
What are you talking about? We don’t need drugs. Getting the measles cures cancer, and you can just take some cod liver oil to feel better (Obviously sarcasm—these claims are false.)
Unfortunately maga will never see this and even if they did they won't believe it.
So no more new drugs....
The DRUG COMPANIES sure don't have the money to do any research. They've got ADS to run.
Lab research is designed to pill rather than cure, they want money in return.
Thank you Mr. Cuban. We should realize that cutting NIH funds will have very adverse outcomes. Even withdrawing from WHO and other organizations will have trouble. Elon Musk was highly disruptive. DJT is also highly disruptive.
We’re going to have to rely on other countries for medical research (and most other scientific work, frankly) for the foreseeable future. The GOP will quash all of it here.
NIH is the best investment the government can make. www.forbes.com/sites/michae...
Bingo! This is why defunding nih is crucial and its imperical research teams leaves us open to the snake oil salesman.
Mark Cuban = Truth Teller
Why then is the pharmaceutical industry still charging us so much for our medications?
Quite the fallacy that innovation is the realm of business, it is seeded by government and academic research. Even within business, they claim the innovation of workers as their own, often denying them it's value. Short-term profit interests squelch true innovation
Thank you for all the good information you post.😍
Yes NIH research will, like many things, be missed. However these new drugs all have “side effects” that are worse than the underlying conditions. Why are soooo many new drugs appearing? Many for “diseases” that have been fabricated as well
These are the same drugs saving lives!
🏥⚕️💉🩸💊😷🩺
Growing up, I was aware of headlines about Britain's brain drain - the best and the brightest attracted to mainly the USA - perhaps Trump might precipitate an American brain drain - the UK and Europe could benefit.
Democrats move us forward. Republicans move us backward ( while they slide their hands into your wallets). Bankrupting America while plundering its resources seems like a very conservative thing to do.
RFKjr doesn't believe in any research but his own.
Hey Mark, I hope you’ll be at these protests.
Begging the question of why it is not mandated that a return of a percentage of profits on said drugs go back to fund NIH research.
I truly believe that the whole idea of anti-vax,is to get rid of what the First Felon and Muskrat,believe,is the surplus population.That is exactly why RFK jr. was hired,because he REALLY is against vaccines, and believes his own crazy ideas. Believe me, the people at the top are getting vaccinated.
In my role within the tech transfer field, I have a unique perspective on the journey of medical innovations from the university to market. It is an absolute certainty that pharma companies, will not pick up the costs for the foundational research needed to discover new medical breakthroughs.
Yeah so let's tie the hands of the NIH and render it ineffective.
Now it appears we should chug cod liver oil 🤬
Despite the loud insistence by ideologues like Musk, every study I’ve seen over the past few decades has found the same. Pharma runs the trials, but the actual drug discovery is funded by the govt and done by govt agencies and universities. The patents & profits are just handed to our oligarchs.
Then why does the US government allow these corporations to rip us off for profit when our tax dollars paid for the formulation in the first place?
Gutsick Gibbon (Erica) does a really good breakdown on why basic science is so important, mostly done in universities on grants. It is the BASIS of applied science, which creates the products we use. Applied science wouldn't exist without it.
Let 'em die. That's what "good christians" would do. Says so in Leviticus. (I wonder how many of those can tell me the final, and superseding, commandment that their imaginary friend ordered as reported by Matthew who was born after the model for the "friend" died?)
Really tragic that people at this level in our society have no idea how things worked.
👏👏👏👏👍
trump and musk seem to want to destroy every good thing about our country. Why? Just to pick up and control all the broken pieces?!
Yes - people ARE ALREADY DYING bc of NIH cuts (study participants cut off mid-study!) This (plus Bird Flu etc. we Captain Brainworm in charge of thr CDC) is going to make Covid look like a practice run!
"But we don't need NOAA . . We can get that information on our phones!" "But we don't need NIH . . We can get our drugs from big pharma!"
And even though a majority of funding comes from pharma companies, the NIH funding that trains scientists to work at those companies is essential to drug companies and their employees.
Thanks for starting Cost Plus Drugs. I just purchased a 90 day supply of my anti-cancer drug Imatinib for under $100 (including shipping) from CostPlusDrugs.com. At the drugstore Imatinib is over $1900 for a 30 day supply.
It's just another reason that universal basic income should be seen as a rightful dividend. Since public money went into all of this, we are all shareholders who deserve a fair return on our investment. Same goes for all our data being fed to AI.
With RFK jr in charge, NIH research and the FDA are dirty words.
😡
@mcuban.bsky.social Any chance your pharmaceutical company could fill in some gaps? I'll intern for free.
It makes NO sense for our country to be destroying these departments/agencies. This government is pushing to make its people less healthy, setup to wipe out millions WHEN next pandemic hits. People-stand up and scream, don’t take this!
My mother was set to participate in a cancer study that had to be cancelled due to NIH cuts. These cuts will harm countless people. If I saw Musk or Trump drowning, I wouldn't just not help, I would record it to enjoy later. They are evil men that deserve anything bad that happens to them.
Are we supposed to get our new drugs from Russia now? N Korea?
Also, the retained patents and generated income for NIH. The US needed/ needs to stop funding/subsidizing any industry it doesn t retain IP in or get minimum return on investment. We constantly invest in big business and not people. Also, the MAHA guy is essentially speaking eugenics.
NIH funds basic research to discover how biology works before drugs can be developed and tested. In Shark Tank terminology, this is when the Sharks say, "It's too early, I'm out.". Nevertheless, the ROI for America is massive.
Yet...with this level of funding from Government...Americans have the most expensive health care in the world....seems wrong
If you include UK & EU govt research as being akin to NIH research, imho you'll find that track record stretches back all the way to the 70s. Course, the same is true of every military & commercial passenger/cargo aircraft. etc... Heck, NASA tech spinoffs are worth *Trillions* of dollars.
Excellent!! Thanks for finding this 😘
And you’re part of the problem you wealth hoarding dragon
And for every $1 invested in NIH, we see $2.46 dumped back into our economy. The NIH is good for our health, it’s good for science, it’s good for communities, it’s good for our economy.
Actually no the nih will publish their own papers on topics of their interest using drugs donated by pharmaceutical companies. They do not perform phase one through three clinical trials which are the ones required for approval. NIH is key for rare or unserved patient populations.
@mcuban.bsky.social on top of the health benefits, money spent by NIH is one of the best investments the government makes. For every $1 spent by NIH, $2.56 was generated in return and supported over 400,000 jobs. www.forbes.com/sites/michae...
Who needs scientific research or innovative medicine in a eugenics based Fascist authoritarian dictatorship?
Congress and the Courts must immediately stop this destruction of America’s scientific knowledge and creativity.
Thank you
Republicans are under the spell of a PROFESSED PREDATOR incapable of empathy (without a capacity for shame, an even less regard for godliness.) He’s the cold GOP standard bearer for Republicans. Evil is the new norm. Better angels must keep speaking out. There’s more good in us than doom in them.
Yes, Republicans apparently want us all to die in our 50s. Unless we are rich, white and male of course.
Horrified to be an American right now. Dreamed last night we moved to Ireland and was so sad when I woke up.
The Veterans Health Administration developed the Hepatitis C cure. Just FYI. So many gov’t org’s fund/support amazing research.
Because science matters
Yes of course! We are not dealing with normal people in this administration. We are dealing with people who want to destroy the country and everyone in it.
They don’t care about anything but what benefits them.
Everything is rigged.
A healthy country impedes 47’s slide into a crippled nation dependent on him. He can’t declare Martial Law if people are healthy.
Gila monster venom research, funded by NIH, gave us GLP-1 drugs. The research started in the 1980s and took decades. That definitely would be cut in today’s climate. What will we not have in the future? China certainly benefits in their pharmacological research efforts!
Anti-science is becoming anti life
And we are sicker than ever for it
The cuts to NIH will have long-lasting negative impacts.
People are going to die.
When you aren’t allowed to use “woman”, “women” “female”, “girl”, or “men & women” for any research funding or grant, the US will no longer lead research on anything.
GOP/MAGA/religious zealots want to send us back 2000 years.
I take what's called an orphan drug, it's a drug that treats only one condition so it is not commercially profitable and without the NIH these medications would never be funded researched or approved. It literally saves my life every day.
thank you! succinct and powerful ...I will be sharing everywhere I can
But the pharmaceutical companies reaped the benefits and inflated the prices
Any chance you could help get us updated flu and covid vaccines this fall?
Seems like pharmaceutical companies would be raging against these cuts because now they will need to foot the bill for research previously funded by the taxpayers!!!
Nothing more recent?
Do Trump, Kennedy, anti choice or anti vaxxer care? 💔💔
Approved drugs Used to treat sick people Many of whom are poor,non white, not American born trump : ''why are we keeping these people alive'' ?
Drug companies say they have to charge high prices so they can develop drugs, which has been bs forever. Can’t even afford the drugs we helped to develop, but the big shots have large wallets. All Americans should have the same healthcare as the politicians- free
Aa an epileptic diabetic with family on transplant, heart, and cancer medication, also after losing my father to Alzheimer's, the NIH isextremely important to me
Yeah but who ever benefited from that kind of waste? Oh, crap
A great book on this subject...
Did they research oxycotin
Cuban, please run for President and save your country ….
NIH funded academia research is the lifeline and the intelligence source for the whole biotech/pharmaceutical industry. They are literally killing the entire industry.
Say good-bye to being a leader in scientific and medical research! Our best and brightest will be heading to Europe and Asia to continue their pioneering work to improve medical outcomes.
They also contributed to Covid 19.
It’s too bad the US doesn’t have someone such as yourself in politics, they drastically need someone with actual leadership and common sense along with business acumen to move ahead
“In this cross-sectional study of 356 drugs approved by the US Food and Drug Administration from 2010 to 2019, the NIH spent $1.44 billion per approval on basic or applied research for products with novel targets or $599 million per approval” jamanetwork.com/journals/jam...
@mcuban.bsky.social This recent FB post was from my wife’s experience at NIH recently. She has the same rare disease that took our son. NIH is a national treasure.
They want EVERYTHING privatized. NO more subsidies.
Trump voters don’t care.
The price of their R&D will get passed on to consumers like another tariff
Thank you. If The Drumpf can’t control us, he wants to kill is. Shades of his nephew is in this.
That's OK. They just need to get a guy who can write a really good ai prompt. Don't need experts or money really.
My grandfather was a doctor (WWII GI-bill recipient!) and explained that the cost of medication development is in research. After that, the materials for manufacturing a single drug can vary significantly, ranging from a few cents to several dollars. However, consumers pay wildly inflated prices.
When we put the NIH back together, we need to address the fact that our tax dollars fund drugs that we then have extraordinarily financial hurdles to individually access them.
Trump is eliminating every agency and safety precaution in place that would prevent a dictatorship. Where are our military and secret service with the knowledge to put together a military coup and oust this dangerous felon? A covert operation is desperately needed.
Which also begs the question why those drugs are still expensive when taxpayer money was used to develop them.
Mark keeps hauling our asses back to reality and genuine steps forward. We need more rich guys like him. Although I never watched either show, I'm guessing that Shark Tank and The Apprentice never had much in common. justweighing.com
What if we put signs in drugstores sharing this? Any "brave" pharmacies could put slips into the prescription packets about the benefits of funding NIH and what's lost when it's cut. Short of any company involvement, why not station people in front of pharmacies in red areas sharing this info?
Ask any cancer patient how important this is. Cancer treatments have made great strides in less than a decade.
@mcuban.bsky.social Please connect with @ezrakleinbot.bsky.social and drive supply side progressivism.
I’m pretty sure He, They, Them really didn’t pay attention in science, math, history or any other class that required you to actually study! Once school got beyond trying to color within the lines they gave up and stared out the windows.
Drugs denied as recent as 2020 are now released for use. I wonder who's responsible....
and every single dollar Musk Industries has made is built on a LONG foundation of government investment - i.e., PUBLIC investment; that would be the investment Musk is now systematically dismantling. Trump own this: Only the Best
Which is another reason drug prices should be negotiated down, if the taxpayers helped fund the research, they are also stakeholders of sorts.
Sad to be an American. This isn’t cost & fraud saving; this is pure eugenics.
There’s a wider conversation to be had about drug pricing here. But yes. Drugmakers piggyback off of publicly funded research and it is VITALLY important!
It does make one wonder why the cost of the drugs is so high then. Is it to pay for millions of drug commercials in print/electronic media? Since the doctors who prescribe already have that information, it seems like a giant campaign to pressure doctors by creating panic and false hope in patients.
Big Pharma overcharges for drugs built on publicly funded research --point taken, that’s not equitable. But how does knee-capping the NIH help with the actual high costs of new drugs that aren’t subsidized? Feels like punishing the wrong target.
1/ Yet more evidence of what post new-deal American state was capable of. ARPANET was a publicly funded project. That became the internet. The NIH was essential to building the modern medicine of today. What started in the American public sector become contributions to the world.
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We do not want people healthy; they cause too much trouble.
If taxpayer dollars contributed to the development of any pharmacuticle or treatment then taxpayers should get a say in the price. That seems only fair.
Mr. Cuban, do you think it's the real objective of this new government? How can we, as mere citizens, help this government get it done if we don't really get it yet?
i used to not like you , but you seem to be a good guy a cool guy maybe you just got TOO fired up about the Mavs😜
If you know anyone who is living with Stage IV breast cancer and outliving 2010 Stage IV breast cancer victims ⬆️This is the reason!
They have been instrumental globally in treating and curing major diseases for decades. Such an important point.