ME/CFS Science @mecfsscience.org · Jun 29 1) 🇯🇵 A Japanese group published their hypothesis of Long Covid. They suspect SARSCoV-2 causes a reactivation of another virus (HHV-6B) in the olfactory bulb where it produces a protein (SITH-1) that reduces acetylcholine levels in the brain. Let's have a closer look...
46 likes 2 replies
Replies
2) These researchers had previously done a mouse experiment where SARS-CoV-2 spike (S1) protein in the nasal cavity caused fatigue- and depression-like symptoms and reduced acetylcholine. Symptoms were improved with the drug donepezil (an acetylcholinesterase inhibitor)
Thank you for this interesting thread. I know I had a HHV infection as a child, and my GP wanted to prescribe me an AcCh inhibitor for an unrelated ailment, which I refused because I thought that ailment was not wortrh the side effects. I might reconsider!