ME/CFS Science @mecfsscience.org · 27d 1) 🇧🇪 A Long Covid study from Brussels tested if the 6MIST, a relatively simple exercise test, is a valid alternative to the 2-day cardiopulmonary exercise testing (CPET) that has been used to measure PEM. In brief, the answer was no.
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2) The 6MIST is a portable, and simple exercise test that involves high knee stepping to a metronome rhythm that accelerates every 30 seconds. It's compared to CPET which requires a specialised setup such as stationary bike, measurements of watts and ventilation, etc.
Strange to do a whole study on this. 2-day CPET is already an unreliable way to assess PEM, so what did the authors expect to find out with an unreliable baseline?