Mikel Lavilla-Puerta

@mikellavi.bsky.social

147 Followers 154 Following

Oxygen, yeast, SynBio and sometimes, plants. Postdoc at Oxford Biology, PhD at Scuola Superiore Sant'Anna. I also sing and am very fond of my village.

The synthetic circuit, plus a hypoxia-inducible feedback loop with PCO1 and a copy of RAP. Parameter analysis shows that PCO's features (affinity for oxygen, RAP, etc.) Dictate how fast responses are!
The synthetic circuit is fast! 5 min in, hypoxia is already activating the reporter output!
Synthetic yeast Cys-NDP strategy