Molecular Oncology Almanac

@moalmanac.org

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The Molecular Oncology Almanac (MOAlmanac) is a paired clinical interpretation algorithm and knowledge base for precision cancer medicine.

Molecular Oncology Almanac 2026 May database release
Molecular Oncology Almanac April 2026 database release
2026 March Molecular Oncology Almanac database release
moalmanac.org now points to dev.moalmanac.org
Molecular Oncology Almanac's 2026-02-05 database release
Molecular Oncology Almanac's December 2025 database release.
Molecular Oncology Almanac is now on LinkedIn
Molecular Oncology Almanac interpreter 0.8.4 release. Both COSMIC and ExAC are no longer required datasources to run the algorithm.
Molecular Oncology Almanac's October 2025 database release, including precision oncology market authorizations from September 2025 from the FDA and EMA.
Interpretation algorithm release 0.8.3. A bug fix for an issue that prevented report generation in rare circumstances.
The Molecular Oncology Almanac cloud portal (portal.moalmanac.org) is currently suspended, and perhaps deprecated, due to Google Cloud’s deprecation of the Life Sciences API. It may be revisited at a future date. The algorithm continues to be available through GitHub and Docker Hub. Please contact us if you have any questions, comments, or concerns about this change.
Molecular Oncology Almanac interpreter updated to support Python 3.13.
Molecular Oncology Almanac's May 2025 database release notes.
Molecular Oncology Almanac April 2025 database release notes
Therapy names normalized to NCI thesaurus within the Molecular Oncology Almanac's March 2025 release.
Molecular Oncology Almanac db March 2025 release notes
MOAlmanac release 0.8.1 removed warnings, revised the Docker container to support multiple architectures, updated the underlying moalmanac database, and updated datasource documentation.
MOAlmanac's 2025 February database release included 3 new FDA approvals.