Theobald Smith Society

@njmicrobe.bsky.social

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We are the New Jersey Branch of the American Society for Microbiology. Visit us at https://www.njmicrobe.org

Photo shows Arati Prabhakar, Ph.D., Director of the White House Office of Science and Technology Policy (OSTP), awards Pfizer Inc. representatives Annaliesa Anderson (C) and Alejandra Gurtman (R) the National Medal of Technology and Innovation during an awards ceremony at the Eisenhower Executive Office Building in Washington, DC, January 3, 2025. Photo by Ryan K. Morris
Photo of Arati Prabhakar, Ph.D., Director of the White House Office of Science and Technology Policy (OSTP), awarding Bonnie L. Bassler the National Medal of Science during an awards ceremony at the Eisenhower Executive Office Building in Washington, DC, January 3, 2025. Photo by Ryan K. Morris
An antifungal peptide, Cryptomycinamide (KKOO-NH2), derived from a 9-amino acid segment of the C. neoformans Cdc50 protein. A fungal killing assay indicated that KKOO-NH2 is fungicidal against C. neoformans. The peptide has antifungal activity against multiple major fungal pathogens with a minimum inhibitory concentration (MIC) of 8 μg/mL against C. neoformans and Candida glabrata, 16 μg/mL against Candida albicans and C. auris, and 32 μg/mL against Aspergillus fumigatus.