PCF Science

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The official BlueSky account for scientific news from the Prostate Cancer Foundation. Also on X as @ PCF_Science

Prostate Cancer Foundation 2026 PCF TACTICAL Awards Targeting Mechanisms of Lethal Prostate Cancer REQUEST FOR LETTERS OF INTENT IMPORTANT: Applying for a PCF TACTICAL Award (Therapy ACceleration To Intercept CAncer Lethality) involves a 2-stage process. PCF requires a Letter of Intent (LOI), followed by full application submission upon our invitation. The Prostate Cancer Foundation (PCF) is pleased to announce a Request for LOIs for PCF TACTICAL Awards from qualified teams of investigators from academic and community institutions that will directly contribute to improved outcomes for patients with prostate cancer with lethal potential. These awards will be funded depending on the level of innovation and transformative potential in applications received. PCF seeks high-risk, currently unfunded projects from academic and community research institutions around the world. TACTICAL Awards provide $5 - $10 Million U.S.D. per award over 3–5 years.
Prostate Cancer Foundation 2026 Young Investigator Awards REQUEST FOR APPLICATIONS The Prostate Cancer Foundation (www.pcf.org) champions investment in human capital to fast-forward solutions for prostate cancer with the ultimate goal of ending death and suffering from metastatic prostate cancer. We continue to focus significant efforts on developing gifted cohorts of young prostate cancer researchers. Since 2007, PCF has awarded 469 PCF Young Investigator Awards in 16 countries, making it one of the most prodigious, productive, competitive and prestigious early career awards in cancer research. We are pleased to announce a new round of funding for PCF Young Investigators. We especially encourage young investigators working on prostate cancer health disparities to apply. The mission of PCF is to fund research addressing unmet medical needs in the diagnosis and treatment of potentially lethal prostate cancer.
Prostate Cancer Foundation 2026 PCF Challenge Awards For Prostate Cancer with Lethal Potential REQUEST FOR APPLICATIONS The Prostate Cancer Foundation (PCF) is pleased to announce a Request for Applications for PCF Challenge Awards for Team Science investigations of prostate cancer with lethal potential. These awards will be funded depending on the level of innovation in applications received. PCF seeks high-risk, currently unfunded projects from academic and community research institutions around the world. PCF Challenge Awards: • Should be composed of at least 3 investigators capable of providing unique scientific expertise to the solution of this significant problem in prostate cancer research. • May be assembled from one institution, or several institutions. • Must embed at least one young investigator as an integral contributor to the team. To qualify as a young investigator, this team member must have a doctoral-level degree and be within six years of completion of their terminal degree or subsequent mentored academic or clinical training program including postdoctoral or clinical fellowships.
Prostate Cancer Grant: Deadline December 1, 2025! This grant was created in collaboration with the SNMMI Mars Shot Research Fund and Prostate Cancer Foundation for innovative research addressing unmet medical needs in the diagnosis and treatment of prostate cancer. This is a three-year grant and will provide $75,000 for three (3) years with travel expense to the PCF YI Meeting included. For full details and to submit your application, apply through the official grant portal.
Prostate Cancer Foundation 2025 PCF TACTICAL Awards Targeting Mechanisms of Lethal Prostate Cancer REQUEST FOR LETTERS OF INTENT / FULL APPLICATIONS IMPORTANT: Applying for a PCF TACTICAL Award (Therapy ACceleration To Intercept CAncer Lethality) involves a 3-stage process. PCF requires a Letter of Intent (LOI), followed by full application submission upon our invitation. Following peer review, top applicants will undergo a Zoom-based interview. The Prostate Cancer Foundation (PCF) is pleased to announce a Request for LOIs for PCF TACTICAL Awards from qualified teams of academic scientists that will specifically address the development of 21st Century therapies for lethal forms of prostate cancer. These awards will be funded depending on the level of innovation in applications received. PCF seeks high-risk, currently unfunded projects from academic institutions around the world. TACTICAL Awards provide $5 - $10 Million U.S.D. per award over 3-5 years. • Support large-scale research projects concerning metastatic, lethal prostate cancer over a duration of 3-5 years. • Institutional indirect costs of up to 10% will be allowed and should be included as part of the total research budget. • Clinical trial costs are not allowed; however, correlative research to support high impact clinical trials for advanced prostate cancer is encouraged. IRB submission and preferably approval is desired at time of application.
Prostate Cancer Foundation 2025 PCF Challenge Awards For Metastatic, Lethal Prostate Cancer REQUEST FOR APPLICATIONS The Prostate Cancer Foundation (PCF) is pleased to announce a Request for Team Science Applications for PCF Challenge Awards for investigations of metastatic, lethal prostate cancer. These awards will be funded depending on the level of innovation in applications received. PCF seeks high-risk, currently unfunded projects from academic institutions around the world. PCF Challenge Awards: • Composed of a team of at least three (3) investigators from non-profit academic research centers, including one young investigator (see PCF Challenge Award Team requirements below). • Support large-scale research projects concerning metastatic, lethal prostate cancer over a duration of two years. • Provide up to a total of $1 million per team. • Cover only direct research costs and travel to the Annual PCF Scientific Retreat. • Clinical trial direct costs are not allowed; however, correlative research to support high impact clinical trials for advanced prostate cancer is encouraged. IRB submission and preferably approval is desired at time of application. • All studies involving patients must include plans for including diverse participant populations with appropriate representation of ethnic and racial minority groups. Comprehensive statistical plans and power calculations are required. Research proposals in the following topic areas are solicited: • Theranostics. • Drugging currently undruggable oncology targets: preventing progression to lethal disease. • Improved biotechnologies for precision medicine. • First-in-field immunotherapies for prostate cancer. • Artificial intelligence/machine learning to better inform patient outcomes. • Host microbiome and tumor metabolism.
Prostate Cancer Foundation 2025 Young Investigator Awards REQUEST FOR APPLICATIONS The Prostate Cancer Foundation (www.pcf.org) champions investment in human capital to fast-forward solutions for prostate cancer with the ultimate goal of ending death and suffering from metastatic prostate cancer. We continue to focus significant efforts on developing gifted cohorts of young prostate cancer researchers. Since 2007, PCF has awarded 429 PCF Young Investigator Awards in 16 countries, making it one of the most prodigious, productive, competitive and prestigious early career awards in cancer research. We are pleased to announce a new round of funding for PCF Young Investigators. We especially encourage young investigators working on prostate cancer health disparities to apply. The mission of PCF is to fund research addressing unmet medical needs in the diagnosis and treatment of potentially lethal prostate cancer. PCF Young Investigator Awards will be three (3) years in duration and will provide $75,000 per year. The award funds may be used innovatively and flexibly to advance the career and research efforts of the awardee. This for example, includes funding “protected time” or direct costs for laboratory science. This award does not support indirect costs such as institutional overhead. Every PCF Young Investigator is required to be under the direct supervision of 1-3 mentors. Young Investigator awardees are required to attend the Annual PCF Scientific Retreat and Young Investigator Forum, typically held in October, throughout the duration of their award.
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