Pablo J. Sáez

@pjsaez.bsky.social

1651 Followers 493 Following

Husband - Dad of 2 - Scientist 🇨🇱 Chilean expat. I love to study how cells walk & talk. PI of the @cellcommlab.bsky.social #CellMigration #CellComm #calciumsignaling #organelles 🧪🔬

The video shows an immune cell migrating in a hexagonal array that forces its branching, but the macrophage keeps on moving.
Videomicroscopy of a cell transfected to visualize the endoplasmic reticulum and the microtubules. It is possible to see how the endoplasmic reticulum jumps over a microtubule.
Movie shows the cytoskeleton of a cell that has 2 nucleus, which are joined by membrane bridges.
the movie shows a damaged zebrafish larvae, in which leukocytes have been labeled to observe their migration towards the injury site
the movie shows a cell with a rounded soma (cellular body) and a long protrusion of the membrane, on which mitochondria are spreading to provide energy.
The movie shows an immune cell extending multiple branches in all directions in search for danger signals or pathogens.
The image shows a figure from a publication introducing a new type of vesicles named blebbisomes. First light microscopic pictures show forming blebbisomes, then a large zoom on a forming blebbisome Is shown by electron microscopy. Then other pictures show the actin cytoskeleton, and migrating cancer cells that are releasing blebbisomes
Movies of cells videoed under the microscope of an immune cell interacting with a target cell. It is possible to see a very close interaction, membrane ruffles and cellular deformation during the interaction.
Movie of migrating cells, shows that the nucleus gets stuck when a cell is trying to move under another cell.
the movie shows a rendered cell moving within the extracellular matrix and it shows how the cells decide their path by choosing the lower resistance path
the video shows a rendered cell during migration and it depicts the new adhesion at the cell front and actomyosin contractility
Video of a cell that has a double nuclei. Myosin is stained in green and the DNA in black.
The movie moves an immune cell moving inside microchannels, while they uptake extracellular fluid.
the movie shows the actin cytoskeleton of immune cells during a cellular race within microchannels (micro capillaries). The dendritic cell treated with extracellular ATP moves faster than the untreated one.
The video shows a monolayer of cells moving towards the right to fill a gap made.
The collage shows a montage of a starred cell in different colors.
video showing a motile cell, the membrane is more dynamic at the leading edge
video of an immune cell chasing a bacteria
The video shows a macrophage, a type of immune cell, extending membrane protrusions while exploring its sourroundings
The movie shows the actin cytoskeleton of a migrating cell. It is possible to observe an stress fiber that spans the entire cell, while the membrane moves dynamically.
The movie shows microglia, immune cells to the brain extending branches towards a pipette that releases a danger signal
The movie shows a cell moving towards the right. The actin cytoskeleton is shown in orange a cell-lenght long actin fiber is observed.
landscape satellite image with the name Pablo formed by rivers and mountains