Simon Waddington

@profsimonwad.bsky.social

699 Followers 205 Following

๐˜—๐˜ณ๐˜ฐ๐˜ง๐˜ฆ๐˜ด๐˜ด๐˜ฐ๐˜ณ ๐˜ฐ๐˜ง ๐˜Ž๐˜ฆ๐˜ฏ๐˜ฆ ๐˜›๐˜ฉ๐˜ฆ๐˜ณ๐˜ข๐˜ฑ๐˜บ, ๐˜œ๐˜Š๐˜“ ๐˜Ž๐˜ฆ๐˜ฏ๐˜ฆ๐˜ต๐˜ช๐˜ค ๐˜ต๐˜ฉ๐˜ฆ๐˜ณ๐˜ข๐˜ฑ๐˜ช๐˜ฆ๐˜ด ๐˜ง๐˜ฐ๐˜ณ ๐˜ค๐˜ฉ๐˜ช๐˜ญ๐˜ฅ๐˜ฉ๐˜ฐ๐˜ฐ๐˜ฅ ๐˜จ๐˜ฆ๐˜ฏ๐˜ฆ๐˜ต๐˜ช๐˜ค ๐˜ฅ๐˜ช๐˜ด๐˜ฆ๐˜ข๐˜ด๐˜ฆ๐˜ด ๐˜ˆ๐˜ˆ๐˜, ๐˜ญ๐˜ฆ๐˜ฏ๐˜ต๐˜ช, ๐˜ข๐˜ฅ๐˜ฆ๐˜ฏ๐˜ฐ, ๐˜ฎ๐˜™๐˜•๐˜ˆ ๐Ÿงฌ๐Ÿšฒ

Picture of Simon Waddington as a child and his mother, Anne Maureen Waddington. Year around 1975. His mum is holding a flower for him to look at
Photomicrograph of neurons (top) and astrocytes (bottom)
Left to Right: Anne Cullis, Francis Crick, Donald Caspar, Aaron Klug, Rosalind Franklin, Odile Crick, and John Kendrew
Rosalind Franklin looking down a microscope
A photo of the comic actor, Diane Morgan, reprising her character of Philomena Cunk. Cunk is shown next to a picture of a human skeleton. The excerpted text (from The Guardian review by Lucy Mangan) highlights an interview with UCL's Professor Joyce Harper
Photo of Diamond Beach in Iceland. Black basalt sand in the foreground. Huge blocks of ice on the sand, and even bigger ones in the sea. They are blocks from a glacier, calving ice, from a river that feeds into the sea (calving like a cow, I think?)
Microscopic image of the lens of the eye of a mouse, expressing the jellyfish protein GFP (green fluorescent protein). Looks like an old depiction of a planet in the solar system
Screenshot of paper published by Allfrey, Daly and Mirsky showing depeendence of protein synthesis on RNA
Picture of Marie Maynard Daly at a bench, using chemistry apparatus
Injection of AAV9-DGUOK-GFP into knockout & wild type mice. Graph on left shows number of positive cells. Figure on right shows lots of GFP +ve cells in KO mice, but not wild type, showing repopulation advantage
Hershey and Chaseโ€™s paper finally confirming that DNA is the material of heredity (Hershey AD, Chase M (1952) Independent functions of viral protein and nucleic acid in growth of bacteriophage. J Gen Physiol 36: 39-56.)
Avery, MacLeod and McCartyโ€™s paper showing DNA transforms bacteria from non-virulent to virus strain ( Avery OT, Macleod CM, McCarty M (1944) Studies on the Chemical Nature of the Substance Inducing Transformation of Pneumococcal Types : Induction of Transformation by a Desoxyribonucleic Acid Fraction Isolated from Pneumococcus Type Iii. The Journal of experimental medicine 79: 137-158.)
Picture of Martha Chase (copyright California Institute of Technology).
An adeno-associated viral vector dressed up like a christmas pudding
Figure showing that clodronate liposomes enhance lentivirus-vector gene expression in murine liver after neonatal & adult administration
A picture of a calico cat, crouching in a hole in a wall, surrounded by graffiti
Picture of Florence Bell in the Yorkshire Evening News, Thursday March 23rd, 1939. Captioned "Miss Florence Bell, a 25-year-old graduate of Cambridge University, explaining the fibre test for wool at an exhibition held in conjunction with a conference on industrial physics, which opened to-day at Leeds Univerrsity"
text which says "โ€œPossibly the most pregnant recent development in molecular biology is the realisation that the beginnings of life are closely associated with the interaction of proteins and nucleic acids. Both plant and animal chromosomes, and all the fourteen odd strains of virus which may have so far been isolated in quantities large enough for analysis, have been found without exception to be nucleo-proteinsโ€
Image of the first ever x-ray crystallograph photo of DNA, by Florence O. Bell
Florence Bell's PhD thesis front cover, "X-Ray and the related studies of the structure of the proteins and nucleic acids"
A trichobezoar
A picture of a hairball (a trichobezoar) removed from the stomach of a seven year old child
Nettie Stevens who was one of the first to discover sex chromosomes, looking down a microscope. There are a few jars and stoppered bottles in front and some cupboards behind.
The text of the 1902 paper by William Bateson and Edith Rebecca Saunders which reads: As was stated in the introduction to this paper, with the discovery of the Mendelian principle the problem of evolution passes into a new phase. It is scarcely possible to overrate the importance of this discovery. Every conception of biology which involves a knowledge of the physiology of reproduction must feel the influence of the new facts, and, in their light, previous ideas of heredity and variation, the nature of specific differences, and all that depends on those ideas must be reconsidered, and in great measure modified. If we turn to any former description of breeding experiments we generally perceive at once that the whole account must be re-stated in terms of Mendelโ€™s hypothesis, and that the discussions and arguments based on former hypotheses are now meaningless. As an illustration we may take the account which Darwin gives of his experiments with peloric Antirrhinum
image showing rationale for pathology-specific gene expression