@jhumimmunity.org's July cover (rupress.org/jhi/issue/2/4) highlights the first human biallelic OSMR deficiency. @turveylab.bsky.social et al. show that OSMR deficiency disrupts OSM-STAT signaling, driving severe early-onset #eczema, #eosinophilia, and elevated IgE. doi.org/10.70962/jhi...

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