Biointegrated Photonics Lab

@schubertlab.bsky.social

911 Followers 1075 Following

Science at the interface of biology, chemistry and photonics, discovering new applications of microscopic lasers and sensors. Part of the Humboldt Centre for Nano- and Biophotonics, University of Cologne. PI posting. https://schubert-lab.uni-koeln.de/

A monochrome sketch of a dense layer of biological cells. One cell is shown with more details, including different organelles. The cell also contains a spherical bead that emits a green glow. Red lines and arrows around the bead indicate the biological force that deforms the bead and changes the spectrum of the emitted light from which the absolute force is calculated.

A three panel figure showing microlaser characteristics during dynamic compression by an atomic force microscope.
(a) Lasing spectra acquired during a push and release experiment, where the force applied by the AFM onto the microlaser is linearly increased from 0 nN to 7 nN and then released back to 0 nN. The spectra are normalized and vertically offset to show the shift and broadening of the lasing modes.
(b) Fitted center position of the lasing modes labelled in (a), plotted over the time of the experiment. Two time points right after the microlaser made contact with the beaded tip of the AFM are excluded from the plot due to strong mode splitting.
(c) Fitted FWHM (symbols, left axis) of the 4 laser modes shown in (b) and the measured applied force (pink solid line, right axis) as function of time. The resolution limit of the spectrometer is about 50 pm.

Overview image, showing different microlaser platforms at the top (including disks, spheres, nanorods, and optoplasmonic lasers), the biological targets (cells, organoids, tissue, animals) in the middle, and different applications of microlasers (sensors, optical barcodes, cell tracking) at the bottom.

An image of the title page of an article titled "Biologische und biomedizinische Anwendungen intrazellularer Laserpartikel".