SecureBio, Inc. @securebio.org · Apr 13 When SCV2 first started spreading it wouldn't have been in our databases yet, and the closest would have been bat SARS coronavirus ZC45, uploaded in early 2018. It aligns well to ZC45 along most of its genome, with the exception of the first half of the spike protein.
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Since 95% of the SCV2 genome matches a known genome in the SARS family, our Clades of Concern algorithm would have flagged it relatively easily.