Sergey Ovchinnikov @sokrypton.org · Jun 15

To get OpenFold3 (pytorch weights) working in AlphaFold3 (jax code base) was not super easy. Required an entire weekend and $40 of Claude Code credit. See breakdown of what had to change in AF3 code base to get OF3 weights to work: github.com/sokrypton/al... Commit: github.com/sokrypton/al... (2/3)

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Sergey Ovchinnikov · Jun 15

Finally, the code for anyone wanting to run alphafold3 locally with openfold3 weights (including convert script) can be found here: github.com/sokrypton/al...