TRIDENT Preclinical Trials

@tridentpct.bsky.social

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Multi-site, transformative preclinical evaluation of novel neurotherapeutics through a Government of Canada $24M New Frontiers In Research grant. Check out our website tridentpreclinicaltrials.org for more info or email info@tridentpreclinicaltrial.org!

Three smiling people stand together in front of a purple Western University Schulich School of Medicine & Dentistry backdrop. The person on the left wears a teal sleeveless dress, the person in the centre wears a black floral dress with a light beige cardigan, and the person on the right wears a burgundy short-sleeved dress. They have their arms around one another, smiling at the camera during a university event.
Kruti Joshi, a trainee with the TRIDENT Imaging Team, stands smiling in front of her research poster at the 2026 Robarts Research Retreat. The poster presents findings from a study examining cognitive differences observed during awake and anesthetized mouse fMRI imaging and includes brain scans, figures, and data visualizations. The photo was taken in a conference poster session area, highlighting trainee-led neuroscience research and knowledge sharing.
Kruti Joshi, a TRIDENT trainee from Western University, stands beside her research poster at OHBM 2026. The poster, titled "Investigating Cognitive Differences across Awake & Anesthetized Mice Imaging using fMRI," presents neuroimaging findings comparing cognitive performance under different imaging conditions. Kruti wears a black dress and conference badge and smiles in front of the poster during the international neuroscience conference.
TRIDENT Pride Month graphic featuring the TRIDENT logo and wordmark in rainbow colours on a clean white background. Flowing rainbow ribbons frame the top left and bottom right corners. Centered text reads, “Diverse Collaboration. Stronger Discovery.” Above the slogan is a small rainbow heart icon. The graphic celebrates Pride Month and highlights TRIDENT’s commitment to inclusion, diversity, collaboration, and innovation in neuroscience research. A rainbow heart accompanies the text “Happy Pride Month” at the bottom.
A video of a woman and two children running on a track with a sign reading TRIDENT followed by a photo of the group at a table.
A speaker presents at a podium in a modern conference room at Western University during a neuroscience-related event. A large presentation slide titled “Focus of my research: Translational Cognitive Neuroscience” is projected behind her, featuring text about cognition, disease, and translational research alongside illustrative graphics. Audience members are seated around the room listening attentively, with microphones and conference tables visible in the foreground.
Wide-angle view of a seminar room filled with attendees seated and facing a projected presentation screen at the front of the room. A presenter stands near the podium while a “Thank you!” slide is displayed, featuring acknowledgements and logos from TRIDENT, Western BrainsCAN, and Schulich Medicine & Dentistry. The room has dimmed lighting, ceiling projectors, and an engaged audience listening to the neuroscience presentation.
A speaker standing in front of a podium at the Dementia Disrupted event, with slides in the background "Dementia: A Major Health Challenge in Canada". Audience members sit in front of the speaker.
TRIDENT MIND booth at the Western Science Rendezvous 2026 event
Large graffiti-style “TRIDENT × MIND Discovery Dock” mural mounted on an indoor wall. The artwork features bold purple lettering outlined in black and blue, with paint splatter effects, a blue trident graphic on the left, and a stylized purple brain illustration on the right. The mural has an energetic street-art aesthetic with black, blue, and purple tones against a textured concrete-style background.
A simple cartoon illustration of Kirby, a round pink character with small oval eyes, rosy cheeks, and a smiling open mouth. Kirby is wearing a gold crown with colorful jewels and has short arms and red oval feet, standing against a plain light background.
A black desk background with the text “Happy Administrative Professionals Day!” in white lettering. Office items including glasses, a notebook, pens, and part of a keyboard are arranged on the left, with a pink hibiscus flower on the right.
Three women stand side by side indoors against a neutral wall, smiling at the camera. The woman on the left wears a navy dress with a lanyard, the woman in the center wears a red blouse and black pants, and the woman on the right wears a black long-sleeve top with brown pants. A glass wall or doorway is visible to the right.
A woman in a black dress standing outside the OECD Headquarters building in Paris, France.
Short video showcasing the TRIDENT Knowledge Exchange Group (KEG) meeting held April 8, 2026 at Robarts Research Institute. Slides and visuals highlight three featured talks: Dr. Ariel Batallan Burrowes on ApoE and APP interactions in pattern separation (mouse Alzheimer’s pathology/cognition), Dr. Amr Eed on phosphorylated alpha-synuclein and brain connectivity changes in M83 mice (imaging), and Luke Smolders on advancing data management standards and fMRI implementation. The video emphasizes collaboration across teams in neuroscience research, integrating pathology, imaging, and data science.
Panel discussion in a lecture hall at Western University featuring four speakers seated at the front, with two Western BrainsCAN and Research Community Impact banners behind them. One panelist speaks into a microphone while others listen, and a large screen above shows virtual participants joining via video call, highlighting a hybrid in-person and online event.
A group of attendees sitting in the Brainhack Western event, with the presentation board showing a multi-coloured pixelated brain graphic.
Video begins with a close-up of a camera lens in coloured lighting, then shows a series of scenes from a neuroscience workshop where researchers and participants gather in a shared space, listen to speakers, engage in group discussions, and participate in interactive activities focused on open science, outreach, and science communication.
A picture of 7 people eating dinner together.
Promotional graphic with a purple and blue science-themed background featuring a glowing brain, DNA strands, and capsules. Large text reads “TRIDENT X MIND Discovery Dock” and “Visit Our Booth!” Below, logos for TRIDENT, Science Rendezvous, and MIND appear alongside the event date “May 9th, 2026.”
Seven researchers and industry experts sit in white armchairs on stage at AD/PD 2026, engaged in a fireside debate on whether startups, big pharma, or academia will drive the future of neurodegeneration drug discovery, with a live projection displayed above.
Illustrated graphic recording explaining the TRIDENT research platform (The TRanslational Initiative to DE-risk NeuroTherapeutics). The artwork combines hand-drawn text and icons showing key concepts: collaboration among researchers and emerging leaders, feedback and idea sharing, and sustainable research practices. A microscope, DNA strand, and molecular diagram represent laboratory science and open data practices. A central diagram shows how potential therapies are tested across three platforms—human iPSC organoids, mouse models, and marmoset models—to identify promising molecules. Additional notes highlight sex-based analysis+, high-quality robust data management, and the global importance of neurodegenerative disease research. Logos of the Government of Canada and the New Frontiers in Research Fund appear at the bottom.
Light sheet microscopy video of blood vessels in the brain.
MP Fragiskatos and TRIDENT team photo gallery
A promo video for the TRIDENT Sex-Based Analysis+ Core
A photo of participants in the Western Research Commercial IQ program, listening to a speaker in front of a presentation screen.
A video about the 2026 Centre for Functional and Metabolic Mapping (CFMM) Chili Cook Off Event
A video announcing the release of the TRIDENT e-newsletter, Synaptozone
Picture of a Groundhog with the words "I'm a rodent, not a meteorologist."
A video run through of Montreal, with an overlay and the text "TRIDENT x Montreal."
A photo of the TRIDENT Administrative Core (left to right), Ravi Menon, Sarah Brennan, Sriram Jayabal, Sherry Khan.
A picture of Sriram Jayabal and Sarah Brennan of TRIDENT standing beside an event banner for the Parkinson's Research Day SW Ontario.
A picture of the Ivey Donald K. Johnson Center door and a TRIDENT standing banner.
A snapshot reel showing pictures from the 2024 TRIDENT Annual General Meeting
A picture of the word gratitude against an orange autumnal background
A video of students, trainees, and professors interacting at the a Working With Media Relations training session.
A video promoting the TRIDENT Sex-Based-Analysis+ Core, an integral part of TRIDENT that advises on how to effectively incorporate sex, and other aging-related hormonal milieu differences into the research study design and analysis at every stage of our research. The Core is led by Dr. Liisa Galea with a team of researchers at the Galea Lab at the Centre for Addictions and Mental Health, and aims to discover key knowledge gaps to expand our understanding and avenues to sex-specific treatments.
A graphic image of Dr. Bonnie Lee, Postdoctoral Fellow, TRIDENT SBA+ Core, and the words, "HQP Spotlight"
An image of the globe and a network of people with the text #openscience Week.
A picture of a purple ribbon and the text Wold Alzheimer's Day 21 Sep
A picture of a presenter at the MIND Platform lunch and learn
A graphic image of Medhinee Malavankar, PhD student with the TRIDENT Mouse Core, accompanied by a quote.
A video explaining about TRIDENT and the who, what, where of the project
A picture of 3 TRIDENT team members at the Walk for Parkinsons event.
A purple graphic with a brain and the text World Alzheimer's Month.
A photo of TRIDENT Operations Director Sarah Brennan and Michael J. Fox.
QR code for the TRIDENT Preclinical Trials Instagram account