Vollum Institute

@volluminstitute.bsky.social

142 Followers 54 Following

The Vollum comprises a vibrant and diverse scientific community focused on understanding fundamental biological mechanisms: https://www.ohsu.edu/vollum-institute

This cryo-EM structure of acid-sensing ion channel 1a, known as ASIC1a, reveals a previously unidentified conformational state. The gray lines represent the boundaries of the cell's membrane, showing how the protein sits within it, with the “out” label indicating the side facing the outside of the cell (extracellular) and “in” representing the inside (intracellular). (OHSU/Baconguis lab)

Dr James Frank head shot

Waves of calcium, revealed by a fluorescent dye, ripple across a bed of astrocytes, showing that the cells actively signal. Warmer colors represent higher calcium concentration. The video was sped up from the original. Its resolution was enhanced using AI with the creator’s consent.

Four female scientists posing for group photo in their research lab

Head shot of Hoa Trinh on the left and head shot of Jed Syrenne on the right

Left to right: Laurence Trussell Ph.D., Natalie Sheldon, Chengli Fang Ph.D., Jumi Park Ph.D. and Eric Gouaux Ph.D.; Cathy Spangler Ph.D. is not pictured.