Xavier Grau-Bové 🌾

@xgrau.bsky.social

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Evolutionary biologist. Postdoctoral Fellow & LCF Junior Leader at CRG (Barcelona). «Ara mateix / enfilo aquesta agulla amb el fil d'un propòsit que no dic / i em poso a apedaçar.» xgrau.github.io & ecoevo.social/@xgrau

A summary of the FACS sorting strategy used to isolate alga-positive cells. To the left, a series of scatter plots showing various FACS optical parameters and gates used to isolate the alga-positive cell population. To the right, two pictures, one showing alga-positive host cells (top), and another free-living symbionts (bottom).
Timing of activation of the heat stress transcriptional response per cell type, measured as the amount of transcriptional dissimilarity from the baseline control conditions. The picture consists of a heatmap with cell types as rows and stress timepoints as columns. Rows are sorted by the maximum divergence from the control.
Two histograms showing the level of expression of two gene modules associated with stress (oxidative stress and protein folding, and mitochondrial/nucleolar remodelling). Each of them shows a series of dots (metacells or clusters of similar single-cell transcriptomes) colour-coded by heat stress time-point (from control to recovery) and sorted by cell type. This plot highlights how these two modules are activated in concert across multiple cell types.
A schematic depiction of the experimental time-course of this study: corals are sampled at a baseline temperature of 25ºC, and then again after 6h, 48h and 7 days of heat stress at 32ºC; finally, they're left to recover at 25ºC for 45 days and sampled again.
NOAA Coral Reef Watch daily risk map for the 28th of August, 2023. The map shows at least Watch risk status for most of the Northern hemisphere, including Warning-level or higher in the Northern Atlantic, and Alert Level 1 or higher in the Mediterranean and Red Sea. https://coralreefwatch.noaa.gov/satellite/research/coral_bleaching_report.php
Close-up picture of a Stylophora polyp, with tiny brown dots all through its surface corresponding to Symbiodiniaceae photosynthetic algae — its symbionts. Picture by Shani Levy.
Stylophora pistillata colony from the Red Sea. Picture by Hagai Nativ.
Two boxplots showing the similarity (measured with Pearson's correlation coefficients) of each cell type's expression quantification level between an artificially worsened version of the C. elegans genome (without 3' UTRs) and the GeneExt-rescued version (with reconstructed 3' UTRs)
To the left, a mock browser track illustrating GeneExt in action: gene expression is measured mostly at the 3' end of the gene, which leaves out many transcript from an un-annotated 3'UTR. To the right, the GeneExt logo.
The coral symbiosis and immunity lab is looking for PhD and MSc students to study coral-algal symbiosis, coral innate immunity, stress response and applications in marine biotech. The lab is led by Shani Levy and located in the School of Marine Sciences in Haifa, Israel.
Partial snapshot of Figure 2 from the linked paper, showing the distribution of lineage ages for various coral taxonomic categories (from order Scleractinia to various families), together with environmental variables along the same timeline and reconstructed ancestral states for various traits (coloniality, symbiotic relationships, depth...).
Snapshot of the database entry for the single-cell transcriptomic atlas of Oculina patagonica, showing a UMAP 2D dimensionality reduction and a few of the available options.
Close-up picture of a bleached Oculina polyp. It looks mostly transparent, with just a couple of yellow-brownish dots on it — the few remaining algae.
Picture of an Oculina patagonica colony. Some of the individual polyps in the colony have a brown-yellow colour, indicating that they harbour symbiotic algae. Others are completely white and lack algae.
Close-up picture of an Oculina patagonica colony, with some polyps in a symbiotic state (the brown ones) and some in a bleached aposymbiotic state (white). By Shani Levy.
The first photographs of the stalked jellyfish Depastrum cyathiforme, (Pollachar, South Uist, June 2023). Pictures by Neil Roberts, taken from the linked article.
UMAP 2D projections of single-cell ATAC atlases of a Nematostella gastrula (left) and an adult specimen (right)
Gaudí plots projecting ATAC-seq, H3K4me3 and exon annotation signals onto a two-dimensional Kamada–Kawai graph layout representing genomic contact points. Part of figure 3 in the paper.
Figure 1 from the paper, with two panels. Panel a shows a schematic cladogram of the eukaryotic tree of life with an adjacent table showing the presence/absence of various histone post-translational modifications in various lineages. Panel b is a summary of the multiplexing strategy for ChIP-seq experiments developed in the paper.
Logo of the Biodiversity Cell Atlas initiative
9 UMAP plots showing gene expression values for different genes in the form of a heatmap.
Nematostella vectensis specimen. Photo by Robert Aguilar, Smithsonian Environmental Research Center. From Wikimedia.
A paperback copy of Carl Sagan’s Cosmos