David Tomaz, PhD 🧬 Immune aging is not just chronological age. A human atlas links CD8 memory-cell states to health trajectories; UK Biobank associations used a protein-based proxy, not direct cell counts. doi.org/10.1016/j.im... #Immunology
Immunology
by @moderation.medsky.network
A Medsky feed for healthcare workers in the field of Immunology. Use keywords ImmunoSky or Immunology to have posts included on the feed. Add a @medsky.social Immunology label to be included in the curation list. Posts in reverse chronological order.
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David Tomaz, PhD 
Waggoner Lab Lipid-engineered antibody-based therapeutics target inflamed joints and lymph nodes to enhance rheumatoid arthritis treatment @cp-cellrepmed.bsky.social www.cell.com/cell-reports...
Waggoner Lab Lymph node lymphangiogenesis encapsulates activating germinal centers to constrain their size, which enhances clonal selection and protective antibody responses @cp-immunity.bsky.social www.cell.com/immunity/ful... @carlanowosad.bsky.social @thelundlab.bsky.social
Waggoner Lab CD8+ Tem GZMK+ to GZMB+ ratio distinguishes healthy from disease-associated trajectories and predicts mortality risk @cp-immunity.bsky.social www.cell.com/immunity/ful... @washumedicine.bsky.social @nationwidekids.bsky.social @kingscollegelondon.bsky.social
Waggoner Lab Microglia drive alcohol-induced sedation, motor impairment, and synaptic and neuronal loss through MyD88-dependent perisynaptic extracellular matrix disruption @cp-immunity.bsky.social @davalos.bsky.social @clevelandclinic.bsky.social @evipaouri.bsky.social www.cell.com/immunity/ful...
Waggoner Lab NK cells contribute to early inflammatory responses induced by mRNA vaccination, yet their depletion does not impair the magnitude of long-term adaptive immune doi.org/10.1093/jimm... @jimmunol.bsky.social
Waggoner Lab Influenza A virus infection induces immune dysregulation in the placenta and fetus without vertical transmission in nonhuman primates www.science.org/doi/10.1126/...
Waggoner Lab Extracellular matrix–targeted TNC-scFv armoring enhances CAR T cell persistence and antitumor activity in solid tumors doi.org/10.1126/scia...
Waggoner Lab Adjuvant-induced prophylaxis with CpG oligodeoxynucleotide-schizophyllan complex is a promising approach to enhancing host resistance against respiratory virus infection doi.org/10.1126/scia...
Waggoner Lab Canonical Wnt induction by OTULIN prevents keratinocyte death and skin inflammation www.science.org/doi/10.1126/...
Waggoner Lab Spatiotemporal co-regulation of IL2 and TCR receptors reveals early antigen-driven synaptic synergy in human CD8+ T cells @natcomms.nature.com @ox.ac.uk www.nature.com/articles/s41...
Waggoner Lab Anti‑CD28 CAR T cells largely sparing CD8 T & NK cells while preferentially depleting CD4 T cells in T lineage malignancies, particularly TH2 + TH17 www.nature.com/articles/s41... @natcomms.nature.com @lmu.de
Waggoner Lab Immune genetic associations of antibody Fc-profiles across twins @natcomms.nature.com @ragoninstitute.bsky.social #Alter #Lauffenburger www.nature.com/articles/s41...
Waggoner Lab Review @natrevimmunol.nature.com LAG3 checkpoint function and its mechanism of action in therapeutic targeting www.nature.com/articles/s41...
Suitch 🔬 Immunology | Red nacional de inflamación REI - RICORS (RD24/0007/0004). CPI-26-567 @ University of Valencia How does the body transition from helpful, temporary inflammation to chronic, damaging disease? https://euraxess.ec.europa.eu/jobs/471494 #Immunology #ImmunologyJobs
Fran Bottanelli It is so great to see your science kids spread their wings! And they anyways always come back to visit! @probablycarmen.bsky.social is following her immunology dreams @cipfvalencia.bsky.social while @petia-adarska.bsky.social is starting a post doc in the García-Sáez group at the @mpibp.bsky.social!
JAMA Network Open Among patients with #Melanoma treated with adjuvant anti–programmed cell death protein 1 therapy, chronic immune-related adverse events were common, and later onset and corticosteroid-treated events were associated with chronicity. ja.ma/4ydFY8e
JAMA Neurology Among patients with relapsing #MultipleSclerosis, earlier and continuous ocrelizumab treatment was associated with better long-term relapse and disability control than delayed initiation after interferon beta-1a. ja.ma/3TOyWso
The Journal of Immunology Data provide new insights into a subpopulation of invariant natural killer T (iNKT) cells and demonstrates that the Fgd5 reporter mouse model can be used as a powerful tool to study iNKT cell biology. Find more in The JI: https://ow.ly/ZsgJ50ZUUMp.
University of Oxford Department of Paediatrics We're hiring a Senior Postdoctoral Immunologist! Join @ovg.ox.ac.uk to investigate how immune responses to vaccines differ with age and immunosuppression. 📅 Apply by 28 October 🔗 https://f.mtr.cool/zrnr0ljlz4 #Immunology #Postdoc #OxfordJobs